Home
MDCAT
Biology
Respiration
Respiration MDCAT MCQs with answers
39 past paper MCQs from Biology unit 13,
Respiration, across 1 topic. They are arranged topic by topic; bigger topics show a
sample here and link to their full set and to study notes. Tap “Show answer” for the correct option and a short solution.
Human Respiratory System
1. Respiratory surfaces exhibit which characteristic? (MDCAT 2022)
it must be permeable it must be thick for low diffusion it should be non-vascularized it should have a low surface area
Show answer
Correct answer: (a) it must be permeable
Gases must pass through it, so it is thin, moist, permeable and richly supplied with blood.
2. Smooth muscles are found in all of the following except the: (MDCAT 2023)
trachea bronchi bronchioles alveoli
Show answer
Correct answer: (d) alveoli
The alveolar wall is one cell thick, for gas exchange, and carries no muscle.
3. The method of bringing oxygenated air into contact with a gas exchange surface is called: (MDCAT 2023)
photorespiration ventilation gas transport respiration
Show answer
Correct answer: (b) ventilation
Ventilation is the movement of the medium over the surface; respiration is what the cells then do with the oxygen.
4. About 70% of the carbon dioxide is carried in the blood as: (MDCAT 2024)
carbonate bicarbonate carbaminohaemoglobin dissolved gas in plasma
Show answer
Correct answer: (b) bicarbonate
Most of it travels as hydrogen carbonate ions in the plasma.
5. The range of normal total lung capacity in humans is: (MDCAT 2024)
5-6 litres 8-9 litres 10-11 litres 12-13 litres
Show answer
Correct answer: (a) 5-6 litres
Total lung capacity is about 5 to 6 litres in an adult.
6. The primary function of larynx is: (UHS MDCAT 2025)
Humidifying air Filtering dust Gaseous exchange Voice production
Show answer
Correct answer: (d) Voice production
The larynx carries the vocal cords, so it is the voice box.
7. Which of the following best describes Inspiratory Reserve Volume (IRV)? (KMU MDCAT 2025)
The volume of air forcibly exhaled after normal tidal volume The volume of air remaining in the lungs after tidal The volume of air exchanged during normal breathing The volume of air forcibly inhaled after normal tidal volume
Show answer
Correct answer: (d) The volume of air forcibly inhaled after normal tidal volume
The inspiratory reserve is the extra air that can still be drawn in after a normal breath.
8. During gaseous exchange in human respiration, enzyme carbonic anhydrase is directly involved in the: (KMU MDCAT 2025)
Release of oxygen from hemoglobin Combination of water with carbon dioxide Breakdown of oxyhemoglobin Binding of oxygen to myoglobin
Show answer
Correct answer: (b) Combination of water with carbon dioxide
Carbonic anhydrase of the red cell joins carbon dioxide to water to give carbonic acid.
9. What happens when the external intercostal muscles contract during inhalation in humans? (KMU MDCAT 2025)
The rib cage compresses The ribs move outward The sternum moves inwards The diaphragm muscles relax
Show answer
Correct answer: (b) The ribs move outward
The external intercostals swing the ribs up and out, enlarging the chest.
10. The primary effect of smoking on the respiratory system: (KMU MDCAT 2025)
Increased lung function due to presence of nicotine Reduced risk of lung cancer due to tolerance Damage to alveoli reducing gaseous exchange Improves oxygenation of the blood by activating hemoglobin
Show answer
Correct answer: (c) Damage to alveoli reducing gaseous exchange
Smoke destroys the alveolar walls, so the surface left for gas exchange shrinks.
11. Which protein is present in the walls of alveoli? (NUMS MDCAT 2025)
Collagen Hemoglobin Myoglobin Myosin
Show answer
Correct answer: (a) Collagen
The alveolar wall is a thin sheet of collagen and elastin fibres under the squamous epithelium.
12. The main function of the pharynx in respiratory system: (SIBA MDCAT 2025)
Serves as passage for both food and air Produces mucus Produces voice Filters air
Show answer
Correct answer: (a) Serves as passage for both food and air
The pharynx is the shared passage behind the mouth through which both food and air travel.
13. About 70% of the carbon dioxide is carried in blood as: (UHS MDCAT 2024)
Carbonate Bicarbonate Tricarbonate Carbonic anhydrase
Show answer
Correct answer: (b) Bicarbonate
Most carbon dioxide is carried as hydrogen carbonate ions in the plasma.
14. Range of normal total lung capacity in humans is (UHS MDCAT 2024)
5-6 liter 8-9 liter 10-11 liter 12-13 liter
Show answer
Correct answer: (a) 5-6 liter
Total lung capacity in an adult is about five to six litres.
15. Most CO2 in blood is transported as bicarbonate ions. Choose the event NOT taking place during gaseous exchange at tissue level: (NUMS MDCAT 2024)
Formation of HHb Formation of sodium bicarbonate Formation of oxyhemoglobin Chloride shift
Show answer
Correct answer: (c) Formation of oxyhemoglobin
At the tissues oxyhaemoglobin is giving up its oxygen, not being formed.
16. The respiratory surfaces exhibit following characteristic? (UHS MDCAT 2023)
It must be permeable It must be thick for low diffusion It should be non-vascularized It should have low ventilation mechanism
Show answer
Correct answer: (a) It must be permeable
Gases must pass through it, so it is thin, moist and permeable.
17. The area between the two lungs is called: (SZABMU MDCAT 2023)
Periosteum Infundibulum Mediastinum Hilum
Show answer
Correct answer: (c) Mediastinum
The space between the lungs, holding the heart and great vessels, is the mediastinum.
18. The percentage of CO2 carried as carboxyhemoglobin is? (PMC MDCAT 2022)
10 15 23 28
Show answer
Correct answer: (c) 23
About $23\%$ of the carbon dioxide is carried bound to haemoglobin as carbamino-haemoglobin.
19. Which one is a contagious disease (PMC MDCAT 2022)
lung cancer asthma pulmonary tuberculosis emphysema
Show answer
Correct answer: (c) pulmonary tuberculosis
Tuberculosis is spread from person to person in droplets; the other three are not caught.
20. Lungs are spongy due to the presence of million of? (PMC MDCAT 2022)
Alveoli Parabronchi Air sacs Bronchioles
Show answer
Correct answer: (a) Alveoli
The lungs are filled with millions of alveoli, which is what makes them spongy.
21. The following part is common in both the digestive system and respiratory systems of human beings (NUMS MDCAT 2022)
Trachea Pharynx Larynx Oesophagus
Show answer
Correct answer: (b) Pharynx
The pharynx is the shared passage for food and for air.
22. Which of the following parts of the respiratory system has no cartilage? (NUMS MDCAT 2022)
Larynx Trachea Bronchioles Bronchi
Show answer
Correct answer: (c) Bronchioles
The bronchioles have no cartilage rings, only smooth muscle in their walls.
23. The infection of lungs is called: (PMC Practice 2021)
Emphysema Asthma Pneumonia Bronchitis
Show answer
Correct answer: (c) Pneumonia
Pneumonia is inflammation of the lungs, usually from infection.
24. Breathing is considered as a: (PMC Practice 2021)
Chemical process Biochemical process Mechanical process Both A and B
Show answer
Correct answer: (c) Mechanical process
Breathing is the muscular movement that ventilates the lungs, a mechanical process.
25. The voice box leads to the trachea which is also called (PMC Practice 2021)
Bronchi Bronchioles Windpipe Alveolar duct
Show answer
Correct answer: (c) Windpipe
The trachea is commonly called the windpipe.
26. The structural and functional unit of the lungs is: (PMC Practice 2021)
Alveoli Trachea Bronchiole Bronchus
Show answer
Correct answer: (a) Alveoli
The alveolus is where the exchange of gases happens, so it is the functional unit.
27. During the transport of carbon dioxide, blood does not become acidic due to: (PMC Practice 2021)
Blood buffer Neutralization of H2CO3 by Na2CO3 Absorption by leukocytes Non-accumulation
Show answer
Correct answer: (a) Blood buffer
The hydrogen carbonate and protein buffers of the blood take up the protons as they are formed.
28. A disease caused by gradual breakdown of the thin walls of alveoli is; (UHS MDCAT 2019)
Tuberculosis Asthma Emphysema Bronchitis
Show answer
Correct answer: (c) Emphysema
Emphysema is the breakdown of the alveolar walls, which cuts the surface for gas exchange.
29. During inspiration, the space inside the chest cavity is increased due to: (UHS MDCAT 2019)
The relaxation of the muscles of the diaphragm Relaxation of the external intercostal muscles Increased pressure The contraction of the muscles of the diaphragm
Show answer
Correct answer: (d) The contraction of the muscles of the diaphragm
The diaphragm contracts and flattens, which deepens the chest cavity.
30. Which of the following statements is correct about the respiratory pigments? (UHS MDCAT 2018)
Myoglobin and Haemoglobin has higher affinity for nitrogen Cyanide and Haemoglobin has a low affinity for oxygen Myoglobin has more affinity for oxygen as compared to haemoglobin Albumin, Globulin and Globin proteins are present in respiratory pigments
Show answer
Correct answer: (c) Myoglobin has more affinity for oxygen as compared to haemoglobin
Myoglobin holds oxygen more tightly than haemoglobin, so it takes it up in the muscle.
31. During breathing air from Pharynx enters to: (UHS MDCAT 2018)
Trachea Bronchioles Alveoli Bronchi
Show answer
Correct answer: (a) Trachea
Air passes from the pharynx through the larynx into the trachea.
32. The low levels of Surfactant produced by Alveolar epithelium causes: (UHS MDCAT 2018)
Respiratory distress syndrome Emphysema Bronchitis Asthma
Show answer
Correct answer: (a) Respiratory distress syndrome
Without surfactant the alveoli collapse at each breath out, which is respiratory distress syndrome.
33. Gradual breakdown of the alveolar wall leads to which type of disease in a smoker? (UHS MDCAT 2018)
Coronary heart disease Bronchitis Emphysema Asthma
Show answer
Correct answer: (c) Emphysema
Emphysema is the destruction of the alveolar walls, which cuts the surface for gas exchange.
34. The site of gaseous exchange in humans is: (UHS MDCAT 2017)
Bronchioles Trachea Alveolar Sacs Alveoli
Show answer
Correct answer: (d) Alveoli
The alveoli are the thin walled sacs across which the gases pass.
35. The disease in which there is a breakdown of thin walls of alveoli: (UHS MDCAT 2017)
Asthma Emphysema Tuberculosis Cancer
Show answer
Correct answer: (b) Emphysema
Emphysema is the breakdown of the alveolar walls.
36. Gaseous exchange in animals takes place through: (UHS MDCAT 2017)
Active Transport Osmosis Diffusion Active Transport and Diffusion
Show answer
Correct answer: (c) Diffusion
Gases cross the respiratory surface by simple diffusion down their gradients.
37. The amount of CO2 exhaled from lungs during expiration is: (UHS MDCAT 2017)
4% 0.04% 0.4% 0.0045%
Show answer
Correct answer: (a) 4%
Exhaled air carries about four per cent carbon dioxide against $0.04\%$ in the air breathed in.
38. Breathing consists of: (UHS MDCAT 2016)
Four phases Three phases One phase Two phases
Show answer
Correct answer: (d) Two phases
Breathing has two phases, inspiration and expiration.
39. Carboxyhaemoglobin (10-20%) is formed when CO2 combines with: (UHS MDCAT 2016)
Amino group of haemoglobin Iron part of haemoglobin Haem portion of haemoglobin Plasma proteins
Show answer
Correct answer: (a) Amino group of haemoglobin
Carbon dioxide combines with the terminal amino groups of the globin chains.
Human Respiratory System notes →