Human Reproductive System

Human Reproductive System MDCAT MCQs with answers

75 past paper MCQs on Human Reproductive System, from the Reproduction unit of MDCAT Biology. The year each question appeared is shown where known; tap “Show answer” for the correct option and a short solution.

Read the notes first Practise the unit as a quiz

1.Each human testis is divided into: (MDCAT 2022)

  1. 50-100 lobules
  2. 100-200 lobules
  3. 200-300 lobules
  4. 250-300 lobules
Show answer

Correct answer: (c) 200-300 lobules

About 200 to 300 lobules, each packed with seminiferous tubules.

2.Which cells in the human male are responsible for the release of testosterone? (MDCAT 2022)

  1. pituitary gland cells
  2. Leydig cells
  3. Sertoli cells
  4. spermatogonia
Show answer

Correct answer: (b) Leydig cells

The interstitial cells of Leydig lie between the tubules and secrete testosterone.

3.The fertilized ovum is implanted and undergoes further development in the: (MDCAT 2022)

  1. uterus
  2. ovary
  3. oviduct
  4. cervix
Show answer

Correct answer: (a) uterus

It implants in the endometrium of the uterus.

4.What is true about oxytocin? (MDCAT 2023)

  1. it acts on the kidney tubules
  2. it stimulates ICSH
  3. it performs cellular functions
  4. it dilates the milk ducts of the mammary glands
Show answer

Correct answer: (d) it dilates the milk ducts of the mammary glands

Oxytocin contracts the uterus in labour and drives milk out along the ducts.

5.The function of the hyaluronidase enzyme is: (MDCAT 2023)

  1. penetration of the sperm into the ovum
  2. entrance of the sperm into the vagina
  3. entrance of the sperm into the fallopian tube
  4. inactivation of sperms after their failure to fertilize the ovum
Show answer

Correct answer: (a) penetration of the sperm into the ovum

The enzyme of the acrosome digests a path through the coats of the egg.

6.In human females, what is the small, pear-shaped, muscular, distensible, sac-like organ where gestation takes place? (MDCAT 2023)

  1. uterus
  2. kidney
  3. fallopian tube
  4. cervix
Show answer

Correct answer: (a) uterus

The uterus holds and nourishes the embryo through pregnancy.

7.The labour pains to expel the foetus are due to the action of oxytocin on the: (MDCAT 2023)

  1. endometrium
  2. myometrium
  3. perimetrium
  4. ovaries
Show answer

Correct answer: (b) myometrium

The myometrium is the muscular coat of the uterus, and it is what contracts.

8.The female reproductive system consists of all of the following EXCEPT: (MDCAT 2024)

  1. ovaries
  2. oviduct
  3. cervix
  4. seminiferous tubules
Show answer

Correct answer: (d) seminiferous tubules

The seminiferous tubules are in the testis, where sperm are made.

9.Which hormone is responsible for the labour pains in the human female at the time of birth? (MDCAT 2024)

  1. estrogen
  2. progesterone
  3. oxytocin
  4. corticosteroid
Show answer

Correct answer: (c) oxytocin

Oxytocin from the posterior pituitary drives the contractions of the uterus.

10.The fluid secreted by Sertoli cells provides a liquid medium, protection and nourishment to: (MDCAT 2024)

  1. the oocyte
  2. the sperms
  3. the polar body
  4. the spermatogonia
Show answer

Correct answer: (b) the sperms

Sertoli cells nurse the developing sperm inside the seminiferous tubule.

11.The main function of the epididymis is to: (MDCAT 2024)

  1. transport sperms
  2. connect with the urethra
  3. produce semen
  4. hold the process of spermatogenesis
Show answer

Correct answer: (a) transport sperms

Sperm mature and are stored as they pass along it towards the vas deferens.

12.The immediate next stage of spermatogonial differentiation is: (MDCAT 2024)

  1. secondary spermatocyte
  2. spermatids
  3. primary spermatocytes
  4. sperms
Show answer

Correct answer: (c) primary spermatocytes

A spermatogonium grows into a primary spermatocyte before the first meiotic division.

13.Receive, retain and nourish a fertilized ovum is the main function of: (UHS MDCAT 2025)

  1. Cervix
  2. Uterus
  3. Ovary
  4. Oviduct
Show answer

Correct answer: (b) Uterus

The uterus receives the embryo, holds it and nourishes it through the placenta.

14.The process of spermatogenesis occurs in which part of the male reproductive system? (UHS MDCAT 2025)

  1. Seminiferous tubules
  2. Vas deferens
  3. Scrotum
  4. Epididymis
Show answer

Correct answer: (a) Seminiferous tubules

Sperms are made in the seminiferous tubules of the testis and mature in the epididymis.

15.Which layer of uterus nourishes the embryo after implantation? (UHS MDCAT 2025)

  1. Cervical epithelium
  2. Myometrium
  3. Endometrium
  4. Perimetrium
Show answer

Correct answer: (c) Endometrium

The embryo implants in the endometrium, which then feeds it.

16.Fertilisation normally occurs in the: (KMU MDCAT 2025)

  1. Uterus
  2. Ovary
  3. Vagina
  4. Fallopian tubes
Show answer

Correct answer: (d) Fallopian tubes

The ovum meets the sperm in the upper third of the oviduct.

17.Which cells of the fallopian tube moisten and nourish the ovum? (KMU MDCAT 2025)

  1. Ciliated epithelial cells
  2. Non ciliated epithelial cells
  3. Germ cells
  4. Endometrial cells
Show answer

Correct answer: (b) Non ciliated epithelial cells

The non-ciliated (secretory) cells of the oviduct lining make the fluid that keeps the ovum moist and fed.

18.Which testicular cells in a human male with high testosterone level will start the endocrine activity? (NUMS MDCAT 2025)

  1. Interstitial cell
  2. Sertoli cells
  3. Spermatogonial cells
  4. Leydig cells
Show answer

Correct answer: (d) Leydig cells

The Leydig cells lie between the tubules and make testosterone.

19.Which layer of uterus is composed of contractile muscles? (NUMS MDCAT 2025)

  1. Endometrium
  2. Perimetrium
  3. Myometrium
  4. Both endo and myometrium
Show answer

Correct answer: (c) Myometrium

The myometrium is the thick smooth muscle layer that contracts in labour.

20.One of the endocrine glands responsible for failure in ovulation is: (NUMS MDCAT 2025)

  1. Pituitary
  2. Placenta
  3. Thyroid
  4. Adrenal
Show answer

Correct answer: (a) Pituitary

Ovulation depends on the LH surge from the anterior pituitary.

21.In males, which of the following is considered a urogenital organ? (SIBA MDCAT 2025)

  1. Urethra
  2. Ureter
  3. Urinary bladder
  4. Vas deferens
Show answer

Correct answer: (a) Urethra

The male urethra carries both urine and semen, so it serves both systems.

22.The other name for Interstitial cells in male testes is: (SIBA MDCAT 2025)

  1. Leydig cell
  2. Spermatogonia cell
  3. Sertoli cell
  4. Spermatocyte
Show answer

Correct answer: (a) Leydig cell

The interstitial cells between the seminiferous tubules are the Leydig cells.

23.Beside fertilization, the function of fallopian tube is: (SIBA MDCAT 2025)

  1. Nourishment of embryo
  2. Transport of ovum towards uterus
  3. Secretion of female hormones
  4. Implantation of zygote
Show answer

Correct answer: (b) Transport of ovum towards uterus

The cilia and the muscle of the oviduct carry the ovum down towards the uterus.

24.Which of the following hormone is not produced in older women? (SZABMU MDCAT 2025)

  1. Estrogen
  2. Gastrin
  3. Secretin
  4. Renin
Show answer

Correct answer: (a) Estrogen

After the menopause the ovaries stop making oestrogen; the gut hormones go on as before.

25.The part of male reproductive system that maintains the temperature for sperm production is: (SZABMU MDCAT 2025)

  1. Testes
  2. Scrotum
  3. Vas deferens
  4. Epididymis
Show answer

Correct answer: (b) Scrotum

The scrotum holds the testes outside the body, a few degrees below core temperature.

26.Female reproductive system consists all of the following EXCEPT (UHS MDCAT 2024)

  1. Ovaries
  2. Oviduct
  3. Cervix
  4. Seminiferous tubules
Show answer

Correct answer: (d) Seminiferous tubules

Seminiferous tubules are in the testis, which belongs to the male system.

27.Which one of the following hormone is responsible for the labor pains in human female at the time of birth of baby? (UHS MDCAT 2024)

  1. Estrogen
  2. Progesterone
  3. Oxytocin
  4. Corticosteroid
Show answer

Correct answer: (c) Oxytocin

Oxytocin from the posterior pituitary drives the contractions of labour.

28.Fluid secreted by sertoli cells provides liquid medium, protection and nourishment to: (UHS MDCAT 2024)

  1. Oocyte
  2. Sperms
  3. Polar body
  4. Spermatogonia
Show answer

Correct answer: (b) Sperms

The Sertoli cells nurse the developing sperms and feed them.

29.Main function of the epididymis is to: (UHS MDCAT 2024)

  1. Transport sperms
  2. Connect with urethra
  3. Produce semen
  4. Hold the process of spermatogenesis
Show answer

Correct answer: (a) Transport sperms

The epididymis stores the sperms and passes them on to the vas deferens.

30.Immediate next stage of spermatogonia differentiation is: (UHS MDCAT 2024)

  1. Secondary spermatocyte
  2. Spermatids
  3. Primary spermatocytes
  4. Sperms
Show answer

Correct answer: (c) Primary spermatocytes

A spermatogonium grows into a primary spermatocyte before meiosis begins.

31.The ______ in semen facilitate the transport of sperms. (KMU MDCAT 2024)

  1. Androgen
  2. Prostaglandins
  3. Oxytocin
  4. Testosterone
Show answer

Correct answer: (b) Prostaglandins

The prostaglandins of the semen set the female tract contracting and help the sperms along.

32.The acidity of urine is neutralized by? (KMU MDCAT 2024)

  1. Cowpers gland
  2. Prostate gland
  3. Seminal vesicle
  4. Vas deferens
Show answer

Correct answer: (a) Cowpers gland

Cowper’s glands pour an alkaline fluid into the urethra ahead of the semen.

33.The outer layer of uterus is called as: (KMU MDCAT 2024)

  1. Endometrium
  2. Myometrium
  3. Mesometrium
  4. Perimetrium
Show answer

Correct answer: (d) Perimetrium

The perimetrium is the outer serous coat of the uterus.

34.Which of the following would be produced as a result of reduction division during gametogenesis? (NUMS MDCAT 2024)

  1. Oogonium
  2. Primary oocyte
  3. Primary spermatocyte
  4. Secondary oocyte
Show answer

Correct answer: (d) Secondary oocyte

The first meiotic division of the primary oocyte gives the secondary oocyte.

35.Which cells in the human males are responsible for the release of testosterone? (UHS MDCAT 2023)

  1. Pituitary Gland
  2. Hypothalamus
  3. Sertoli cells
  4. Leydig cells or interstitial cells
Show answer

Correct answer: (d) Leydig cells or interstitial cells

The interstitial, or Leydig, cells between the tubules secrete testosterone.

36.Fertilized ovum is implanted and undergoes further development in the: (UHS MDCAT 2023)

  1. Ovary
  2. Uterus
  3. Oviduct
  4. Cervix
Show answer

Correct answer: (b) Uterus

The embryo implants in the endometrium of the uterus and develops there.

37.After fertilization, zygote takes________for its journey from fallopian tube to uterus: (SZABMU MDCAT 2023)

  1. 6-7 days
  2. 3-6 days
  3. 10-12 days
  4. 12-15 days
Show answer

Correct answer: (a) 6-7 days

The zygote takes about six or seven days to reach the uterus and implant.

38.The best temperature forspermatogenesis is: (SZABMU MDCAT 2023)

  1. 37 O C
  2. 30 O C
  3. 32 O C
  4. 35 O C
Show answer

Correct answer: (d) 35 O C

Sperms are made a couple of degrees below core temperature, at about $35^{\circ}\mathrm{C}$.

39.Leydig cells in testes are responsible for: (SZABMU MDCAT 2023)

  1. Testosterone production
  2. FSH production
  3. Sperm production
  4. Testosterone inhibition
Show answer

Correct answer: (a) Testosterone production

The Leydig cells between the tubules secrete testosterone.

40.The hormone responsible for production of sperm cells and male secondary sexual characteristics is: (NUMS MDCAT 2023)

  1. Estrogen
  2. Progesterone
  3. Testosterone
  4. Thyroxin
Show answer

Correct answer: (c) Testosterone

Testosterone from the Leydig cells drives spermatogenesis and the male secondary characters.

41.Leydig cells are responsible for: (NUMS MDCAT 2023)

  1. Testosterone production
  2. FSH production
  3. Sperm production
  4. Testosterone inhibition
Show answer

Correct answer: (a) Testosterone production

The Leydig, or interstitial, cells secrete testosterone.

42.The function of hyaluronidase enzyme is: (UHS MDCAT 2023)

  1. Penetration of the sperm into the Ovum
  2. Entrance of the sperm into the vagina tube
  3. Entrance of the sperm into the fallopian
  4. Inactivation of sperms after their failure to fertilize ovum
Show answer

Correct answer: (c) Entrance of the sperm into the fallopian

Hyaluronidase from the acrosome digests a path through the layers round the ovum.

43.During birth, which of following acts as a birth canal? (PMC MDCAT 2022)

  1. Oviduct
  2. Ovary
  3. Uterus
  4. Vagina
Show answer

Correct answer: (d) Vagina

The vagina is the passage through which the baby is born.

44.Which of the following part of the male reproductive system is located outside the testes? (PMC MDCAT 2022)

  1. Seminiferous tubules
  2. Epididymis
  3. Efferent ducts
  4. Urinogenital duct
Show answer

Correct answer: (d) Urinogenital duct

The urinogenital duct runs outside the testis; the other three lie within it.

45.Which cells synthesize testosterone? (PMC MDCAT 2022)

  1. Adrenal medulla of adrenal glands
  2. Adrenal cortex of adrenal glands
  3. Interstitial cells of testis
  4. Graffian follicle
Show answer

Correct answer: (c) Interstitial cells of testis

The interstitial, or Leydig, cells of the testis make testosterone.

46.The second meiotic division in oocyte is completed during? (PMC MDCAT 2022)

  1. When ovum is discharged from the ovary
  2. Just before fertilization
  3. Before the onset of menstruation
  4. When the oocyte is fertilized by sperm
Show answer

Correct answer: (d) When the oocyte is fertilized by sperm

The second meiotic division is finished only when the sperm enters.

47.Where are Sertoli cells present in the male reproductive system? (PMC MDCAT 2022)

  1. In germinal epithelium
  2. In seminiferous tubules
  3. In seminal vesicle
  4. In prostate gland
Show answer

Correct answer: (b) In seminiferous tubules

Sertoli cells line the seminiferous tubules and nurse the developing sperms.

48.An egg is fertilized in a laboratory and implanted in uterus for development. Which of the following term is related to this procedure: (PMC MDCAT 2022)

  1. Leutinizatioin
  2. Menopause
  3. In vitro fertilisation
  4. Incubation
Show answer

Correct answer: (c) In vitro fertilisation

Fertilizing the egg outside the body and returning it to the uterus is in vitro fertilization.

49.Which of the following is haploid cell? (PMC MDCAT 2022)

  1. Spermatogonia stem cell
  2. Spermatogonium
  3. Primary spermatocyte
  4. Secondary spermatocyte
Show answer

Correct answer: (d) Secondary spermatocyte

The first meiotic division halves the chromosome number, so the secondary spermatocyte is haploid.

50.Which of the following is included in male (PMC MDCAT 2022)

  1. Cervix
  2. Seminepherous tubules
  3. Corpus luteum
  4. Graafian follicle
Show answer

Correct answer: (b) Seminepherous tubules

The seminiferous tubules of the testis are where sperms are made.

51.Which of the following is a hormone produced by the testes? (PMC MDCAT 2022)

  1. Progesterone
  2. Estrogen
  3. Testosterone
  4. Interstitial cell stimulating hormone
Show answer

Correct answer: (c) Testosterone

The Leydig cells of the testis secrete testosterone.

52.If the sperms are too weak to fertilize the egg in oviduct, which of the following procedure can be used to overcome this problem of infertility? (PMC MDCAT 2022)

  1. In vitro fertilization
  2. Incubation
  3. Hatching
  4. Amniocentesis
Show answer

Correct answer: (a) In vitro fertilization

In vitro fertilization brings the sperm and the egg together outside the body.

53.Which one of the following occurs at puberty in boys? (PMC MDCAT 2022)

  1. Ovulation
  2. Pubic hair growth
  3. Hips broaden
  4. Menarche
Show answer

Correct answer: (b) Pubic hair growth

Pubic hair appears at puberty in both sexes; the other three are female.

54.Which of the following is the part of male reproductive system? (PMC MDCAT 2022)

  1. Cervix
  2. Leydig cells
  3. Myometrium
  4. Corpus luteum
Show answer

Correct answer: (b) Leydig cells

The Leydig cells lie between the seminiferous tubules of the testis.

55.The uterus of the female reproductive system opens up to the? (PMC MDCAT 2022)

  1. Placenta
  2. Ovary
  3. Cervix
  4. Oviduct
Show answer

Correct answer: (c) Cervix

The neck of the uterus, the cervix, opens into the vagina.

56.What Is the function of the fluid secreted by Sertoli cells? (PMC MDCAT 2022)

  1. Stimulate spermatogenesis
  2. Stimulates secondary sexual dveleopment
  3. Provides nourishment to sperms
  4. Inhibits spermatogenesis
Show answer

Correct answer: (c) Provides nourishment to sperms

The Sertoli cells nurse the developing sperms and feed them.

57.Where does fertilization occur in human body? (PMC MDCAT 2022)

  1. Ovary
  2. Uterus
  3. Fallopian Tube
  4. Vagina
Show answer

Correct answer: (c) Fallopian Tube

Fertilization takes place in the upper third of the oviduct.

58.In reproduction, semen refers to which of the following? (PMC MDCAT 2022)

  1. Fluid and sperms
  2. Blood cells and plasma
  3. Blood and sperms
  4. Egg and sperms
Show answer

Correct answer: (a) Fluid and sperms

Semen is the sperms together with the secretions of the accessory glands.

59.The union of meiotically produced specialized sex cells from each parents produce? (PMC MDCAT 2022)

  1. Corpus luteum
  2. Embryo
  3. Zygote
  4. Neuroglial cells
Show answer

Correct answer: (c) Zygote

A sperm and an ovum fusing give the zygote.

60.Which of the following part of sperm cell penetrates into the ovum during fertilization? (PMC MDCAT 2022)

  1. Cytoplasm
  2. Nucleus
  3. Acrosome
  4. Mitochondria
Show answer

Correct answer: (c) Acrosome

The acrosome at the head of the sperm digests a way through the coats of the ovum.

61.In the male reproductive system, the hormone involved in the regulation of the rate of spermatogenesis is called: (NUMS MDCAT 2022)

  1. Luteinizing hormone
  2. Follicle-stimulating hormone
  3. Testosterone
  4. Inhibin
Show answer

Correct answer: (d) Inhibin

Inhibin from the Sertoli cells damps down FSH and so holds the rate of sperm production.

62.Cervix is the part of: (NUMS MDCAT 2022)

  1. Vagina
  2. Oviduct
  3. Uterus
  4. Ovary
Show answer

Correct answer: (c) Uterus

The cervix is the neck of the uterus.

63.Human embryo remains enclosed in: (PMC Practice 2021)

  1. Amniotic sac
  2. Placenta
  3. Chorion
  4. Allantois
Show answer

Correct answer: (a) Amniotic sac

The embryo develops inside the amnion, cushioned by the amniotic fluid.

64.The scrotum is responsiblefor·which of the following in the male reproductive system? (PMC Practice 2021)

  1. Synthesis of sperm
  2. Lubrication
  3. Nourishment of sperm
  4. Temperature regulation
Show answer

Correct answer: (d) Temperature regulation

The scrotum holds the testes a few degrees below core temperature.

65.Which one of the following is most likely to occur in a boy during puberty? (PMC Practice 2021)

  1. He produces eggs
  2. His shoulders broaden
  3. The colour of his eyes change
  4. None of these options is correct
Show answer

Correct answer: (b) His shoulders broaden

Testosterone at puberty broadens the shoulders and deepens the voice.

66.The spermatic cord and spermatic duct are? (PMC Practice 2021)

  1. The same
  2. Different
  3. Same in function
  4. Same in location
Show answer

Correct answer: (b) Different

The spermatic duct carries the sperms; the cord is the bundle of duct, vessels and nerves together.

67.Which of the following is not a true characteristic of spermatogonia? (PMC Practice 2021)

  1. They develop into primary spermatocytes through mitosis
  2. They are undifferentiated
  3. They are germ line cells
  4. They are haploid
Show answer

Correct answer: (d) They are haploid

Spermatogonia are diploid; the haploid stage begins with the secondary spermatocyte.

68.Gametes in animals are produced by which of the following? (PMC Practice 2021)

  1. Mitosis
  2. Meiosis
  3. Fission
  4. All of these options are correct
Show answer

Correct answer: (b) Meiosis

Gametes are haploid, so they are made by meiosis.

69.During spermatogenesis, the __________, which are haploid cells eventually mature into spermatozoa/mature sperms: (UHS MDCAT 2019)

  1. Spermatogonia
  2. Primary spermatocytes
  3. Spermatids
  4. Secondary spermatocytes
Show answer

Correct answer: (c) Spermatids

The spermatids are the haploid cells that grow tails and become spermatozoa.

70.Process ensuring the survival of species over long periods of time, even though individual members of the species die. (UHS MDCAT 2018)

  1. Reproduction
  2. Adaptability
  3. Mitosis
  4. Respiration
Show answer

Correct answer: (a) Reproduction

Reproduction is what carries the species on after its members die.

71.In human female, the egg is fertilized in: (UHS MDCAT 2018)

  1. Ovary
  2. Vagina
  3. Oviduct
  4. Uterus
Show answer

Correct answer: (c) Oviduct

Fertilization takes place in the upper third of the oviduct.

72.Which structure from the following is not present in the male reproductive system: (UHS MDCAT 2017)

  1. Urethra
  2. Seminiferous tubules
  3. Vas deferens
  4. Cervix
Show answer

Correct answer: (d) Cervix

The cervix is the neck of the uterus, in the female system.

73.From among the following, which hormone is the interstitial cell stimulating hormone: (UHS MDCAT 2017)

  1. FSH
  2. GH
  3. LH
  4. Prolactin
Show answer

Correct answer: (c) LH

Luteinizing hormone in the male is called interstitial cell stimulating hormone.

74.In human testis, which structure is responsible for carrying sperm from inside the testis? (UHS MDCAT 2015)

  1. Seminiferous tubules
  2. Urinogenital duct
  3. Seminal Vesicles
  4. Vasa efferentia
Show answer

Correct answer: (d) Vasa efferentia

The vasa efferentia carry the sperms from the testis to the epididymis.

75.In which part of female reproductive system fertilization takes place? (UHS MDCAT 2015)

  1. Proximal part of oviduct
  2. Uterus
  3. Placenta
  4. Vagina PLSPOT 18 of 20
Show answer

Correct answer: (a) Proximal part of oviduct

Fertilization happens in the upper third of the oviduct.

More in Reproduction